Cardiovascular disorders are among the leading chronic illnesses. Medications play a pivotal role to control the signs, symptoms and progression of these disorders. However, the outcome of the management is depend on the delivery of the right regimen to the right patient. A recent prospective evaluation of prescriptions among Ethiopian cardiovascular patients have identified that approximately, two-thirds of elderly cardiovascular patients encountered potentially inappropriate prescription which is more significant. The magnitude of inappropriate prescription is aggravated by long hospital stay and large number of medications. Therefore, it is essential to evaluate patients’ medications during hospital stay to reduce the burden of potentially inappropriate prescription. Members of the young professionals’ chronic diseases network-Gondar chapter have been engaged in the acquisition, analysis and interpretation of results on this project.
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As people get older, Chronic diseases become common causes of diseases, having multimorbidity. This will lead to have polypharmacy in older patients contributing to the regimen complexity which can affects patients medication adherence, prescribing quality, adverse drug reaction, health related quality of life and death. All these necessitates a clinical intervention such as deprescribing (reducing inappropriate poly-pharmacy). But such intervention should consider older patients decision/willingness in medication discontinuation process as it may affects the ultimate their clinical outcome. Though this has been extensively explored in developed countries, no attempt was made to explore willingness of older adults with chronic disease for discontinuation of inappropriate medications.
Young Professionals Chronic Disease Network (YP-CDN) Ethiopia chapter, has worked with older patients living with chronic diseases and has identified their priorities for advocacy, and were used as an input for this research project.
Medication safety for older patients with chronic disease requires deprescription of the inappropriate prescriptions.
Find the full article at http://bmjopen.bmj.com/content/8/4/e020590
Novel Oral Anticoagulants (NOACs) are front line medications for the prevention of cerebrovascular accident secondary to cardio-embolism. Recently, NOACs are replacing coumarins since they do not require close monitoring. But, real world evidence was required to evaluate the extent of adherence to these agents. Accordingly, sub-optimal adherence to NOACs was noted based on evidence obtained from a meta-analysis of 1.6 million Atrial Fibrillation (AF) patients. Interventions should be promptly designed to improve the compliance of patients for NOACs. Further, the availability and affordability of these medications should be insured in developing countries to save the lives of individuals who are suffering from AF.
The finding of the study is available from the following link. doi: 10.2174/1570161116666180123111949.