Infective Endocarditis (IE) affects the endothelial lining of the heart. its mortality after medical therapy has been poorly reported. only recently, a meta-analysis of more than 22, 000 subjects revealed the short- and long term mortality of IE. Accordingly, the 30-day mortality was found to be 20% whereas 2 out of 5 individuals die of IE after 30- day follow-up. In addition to its burden on mortality; it complicates to cardiac, renal and embolic events. Risk factors such as rheumatic heart diseases, congenital heart diseases, diabetes and substance use should be appropriately managed to reduce this morbidity and mortality.
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